The growing interest in ecology, is an indication of the collective concern for the biosystems future and the emerging life forms. Transitioning to new ecologies, requires systemic thinking and a reconstruction of design tools. Architectural practice merges with biology, to produce methods of integrating the "living" into the anthropogenic habitat. One of the emerging approaches of biodesign, known as “Growing Design”, indicates the cultivation of microorganisms to produce materiality. The microorganisms evolutionary process is engaged in finding the most successful spatial organization. In the fusion of human and nature design intelligence, biomaterials are produced, which set new parameters to the building practices and the interaction with the built environment. Growing design, encourages small-scale, low cost and low-energy, cyclical processes, and social production of material space, also creating new connections between urban and agricultural habitats.