The current thesis examines the study of a city block as a new operational unit in the Greek cityscape of Athens. The ascertainment that the Greek city presents distinctiveness’s due to its structure composes some fundamental questions which encourage us to observe the city itself. How did the city create? How did the city evolve? What are the potentials of being changed? Settling the concept of density as a pillar and ascertaining that the city is getting under populated, our analysis and our strategic proposal of the city block evolution is presented. Our strategic proposal conforms to the ration of a rule, which tries to aware every time the city needs and transforms into a dynamic regulation. The structural study of a city block focuses on the micro-scale design in an architectural level of the city, trying to answer to the modern questions which emerge every time. In this current thesis, a study of city block 78088 is occurred and furthermore, some strategies of potential development are being discussed. Through the city block 78088, which is an example of solution, we can generalize to a regulation level and embed it to the New General Building Regulation according to the dilution factor [D. F.].