In this research study, the dynamic relationship between architecture and comics is examined, with a focus on their interaction during the design process. The study is focused in the 21^st century in Athens. Initially, a literature review is conducted to define and approach the public urban space, with special reference to the urban space of Athens. Then, relevant sources are selected and gathered to study the characteristics and design methods in comics, including a historical overview of these as means of visual communication. The analysis then moves to exploring and understanding 10 Greek comics from the last 20 years. These comics and graphic novels by 21^st -century Greek creators offer rich case studies where the spatial context directly or indirectly influences the narrative and character development, with architecture particularly included into the storyline. The collected data is organized into logical sections for effective categorization. The study examines the representation of architectural space within the comics and analyzes the role of image as a means of expression and communication in both comics and architecture. Conclusively, the research draws insights into the indirect and direct ways spatial context are used in storytelling, aiming to demonstrate that architecture is a significant tool in comic narration.