The subject of this dissertation is the design of a permanent lunar research station. Man, driven by his desire for exploration, has always dreamed of colonizing other planets outside Earth. It would, therefore, make more sense to focus initially on the nearest celestial body, the Moon. However, the lunar environment is extremely inhospitable to human physiology. Therefore, humans would have to learn how to cope with adverse conditions and with access to very limited resources. Scientists from all over the world, who have been conducting research and experiments for at least the last decade, want to meet this challenge. Based on this and from data taken from research centers such as NASA and ESA, we have designed a base suitable for living and working for researchers and astronauts. More specifically, this base will allow people to stay and work on the moon for short periods of time in order to study and optimize new technologies, test and utilize lunar materials and grow crops. It is designed in a way that utilizes local materials, as well as new technologies and also allows for future building additions if an expansion is needed for the accommodation of more researchers or uses. Architecture plays an important role in all this, as key factors in this project are the structure and configuration of the space, the use of appropriate materials and the solution of all technical issues. After all, if we seek to become interplanetary beings, our initial goal and our first space stop is our nearby Moon.